Disease: Other Creutzfeldt-Jakob disease
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AIF1 P55008 allograft inflammatory factor 1 Calcium-binding protein 1.9E-06 0.521 0.808
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
AQP1 P29972 aquaporin 1 (Colton blood group) Ion channel 2.6E-07 0.467 0.885
BACE1 P56817 beta-secretase 1 Enzyme 0.88 0.559 0.769
CBLL2 Q8N7E2 Cbl proto-oncogene like 2 Enzyme 0.476 0.808
CHI3L1 P36222 chitinase 3 like 1 1.1E-05 0.419 0.885
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
ENO2 P09104 enolase 2 Enzyme 0.38 0.475 0.846
GPI P06744 glucose-6-phosphate isomerase Enzyme 2.8E-06 0.491 0.769
HECTD2 Q5U5R9 HECT domain E3 ubiquitin protein ligase 2 1.00 0.805 0.231
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
MDH1 P40925 malate dehydrogenase 1 Enzyme 0.93 0.682 0.538
MUL1 Q969V5 mitochondrial E3 ubiquitin protein ligase 1 1.9E-06 0.473 0.808
NEFL P07196 neurofilament light 0.488 0.769
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
PRND Q9UKY0 prion like protein doppel 1.3E-02 0.751 0.192
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
PTGS1 P23219 prostaglandin-endoperoxide synthase 1 Enzyme 6.2E-07 0.460 0.885
RARB P10826 retinoic acid receptor beta Nuclear receptor 1.00 0.478 0.846
RASA2 Q15283 RAS p21 protein activator 2 Enzyme modulator 7.4E-31 0.579 0.769
S100B P04271 S100 calcium binding protein B Calcium-binding protein 4.4E-02 0.383 0.923
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SPRN Q5BIV9 shadow of prion protein 0.29 0.839 0.154
STMN2 Q93045 stathmin 2 0.98 0.674 0.500
YWHAH Q04917 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta Chaperone 0.78 0.743 0.269