Disease: Muscle Spasticity
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
NPHP3-ACAD11 NPHP3-ACAD11 readthrough (NMD candidate) 0.663 0.577
ABCC8 Q09428 ATP binding cassette subfamily C member 8 Transporter 8.0E-24 0.474 0.846
SPATA5 Q8NB90 spermatogenesis associated 5 9.1E-20 0.670 0.654
PMM2 O15305 phosphomannomutase 2 Enzyme 1.4E-17 0.535 0.769
TRAPPC12 Q8WVT3 trafficking protein particle complex 12 Enzyme 5.4E-16 0.751 0.385
WWOX Q9NZC7 WW domain containing oxidoreductase Enzyme 1.2E-15 0.453 0.808
SAMHD1 Q9Y3Z3 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 6.5E-13 0.547 0.769
GFM1 Q96RP9 G elongation factor mitochondrial 1 9.3E-13 0.623 0.692
PLA2G6 O60733 phospholipase A2 group VI Enzyme modulator 2.5E-10 0.476 0.846
TUBB3 Q13509 tubulin beta 3 class III Cellular structure 2.6E-10 0.486 0.808
WDR73 Q6P4I2 WD repeat domain 73 2.8E-09 0.610 0.500
ATAD3A Q9NVI7 ATPase family AAA domain containing 3A Enzyme 4.1E-09 0.628 0.692
ISCA2 Q86U28 iron-sulfur cluster assembly 2 2.4E-08 0.743 0.231
AIMP1 Q12904 aminoacyl tRNA synthetase complex interacting multifunctional protein 1 Enzyme 3.0E-07 0.566 0.769
AMPD2 Q01433 adenosine monophosphate deaminase 2 Enzyme 4.5E-07 0.663 0.577
OCLN Q16625 occludin 8.6E-07 0.507 0.846
VPS13D Q5THJ4 vacuolar protein sorting 13 homolog D 1.1E-06 0.769 0.346
PIGQ Q9BRB3 phosphatidylinositol glycan anchor biosynthesis class Q Enzyme 1.4E-06 0.610 0.577
AP4S1 Q9Y587 adaptor related protein complex 4 subunit sigma 1 Transporter 1.7E-06 0.674 0.385
PYCR2 Q96C36 pyrroline-5-carboxylate reductase 2 2.1E-06 0.682 0.462
DARS1 P14868 aspartyl-tRNA synthetase 1 Enzyme 8.5E-06 0.711 0.500
VPS11 Q9H270 VPS11 core subunit of CORVET and HOPS complexes Transporter 1.9E-05 0.633 0.654
KLHL7 Q8IXQ5 kelch like family member 7 4.6E-05 0.581 0.731
TMTC3 Q6ZXV5 transmembrane O-mannosyltransferase targeting cadherins 3 4.6E-05 0.636 0.538
DHPS P49366 deoxyhypusine synthase 1.6E-04 0.670 0.538