Disease: Spastic Quadriplegia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ADAR P55265 adenosine deaminase RNA specific Enzyme 2.6E-02 0.501 0.808
ARX Q96QS3 aristaless related homeobox 0.91 0.516 0.654
ASNS P08243 asparagine synthetase (glutamine-hydrolyzing) Enzyme 9.4E-06 0.595 0.692
CACNA1E Q15878 calcium voltage-gated channel subunit alpha1 E Ion channel 1.00 0.650 0.577
GLYCTK Q8IVS8 glycerate kinase Kinase 9.7E-11 0.751 0.308
IFIH1 Q9BYX4 interferon induced with helicase C domain 1 7.0E-44 0.471 0.808
ISCA2 Q86U28 iron-sulfur cluster assembly 2 2.4E-08 0.743 0.231
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
MRPS22 P82650 mitochondrial ribosomal protein S22 1.5E-05 0.638 0.500
NALCN Q8IZF0 sodium leak channel, non-selective Ion channel 8.5E-14 0.587 0.615
OSTM1 Q86WC4 osteoclastogenesis associated transmembrane protein 1 1.1E-02 0.644 0.577
PCDH12 Q9NPG4 protocadherin 12 2.9E-13 0.722 0.346
PLA2G6 O60733 phospholipase A2 group VI Enzyme modulator 2.5E-10 0.476 0.846
RAB18 Q9NP72 RAB18, member RAS oncogene family 0.91 0.582 0.692
RNASEH2A O75792 ribonuclease H2 subunit A Enzyme 4.2E-03 0.592 0.692
RNASEH2B Q5TBB1 ribonuclease H2 subunit B 3.3E-09 0.595 0.615
RNASEH2C Q8TDP1 ribonuclease H2 subunit C 5.5E-03 0.590 0.731
SAMHD1 Q9Y3Z3 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 6.5E-13 0.547 0.769
SLC19A3 Q9BZV2 solute carrier family 19 member 3 Transporter 0.10 0.610 0.692
SOX10 P56693 SRY-box transcription factor 10 0.99 0.461 0.808
STXBP1 P61764 syntaxin binding protein 1 Transporter 1.00 0.532 0.692
TREX1 Q9NSU2 three prime repair exonuclease 1 0.58 0.517 0.808
TUBB3 Q13509 tubulin beta 3 class III Cellular structure 2.6E-10 0.486 0.808
TUBB4A P04350 tubulin beta 4A class IVa Cellular structure 0.11 0.608 0.615
WARS2 Q9UGM6 tryptophanyl tRNA synthetase 2, mitochondrial 5.1E-02 0.617 0.577