Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
STAT3 | P40763 | signal transducer and activator of transcription 3 | Nucleic acid binding | 1.00 | 0.320 | 0.923 |
VDR | P11473 | vitamin D receptor | Nuclear receptor | 1.7E-05 | 0.352 | 0.885 |
FGFR2 | P21802 | fibroblast growth factor receptor 2 | Kinase | 1.00 | 0.380 | 0.808 |
LMNA | P02545 | lamin A/C | 1.00 | 0.384 | 0.885 | |
PTPN11 | Q06124 | protein tyrosine phosphatase non-receptor type 11 | 1.00 | 0.385 | 0.923 | |
NRAS | P01111 | NRAS proto-oncogene, GTPase | Enzyme modulator | 0.49 | 0.390 | 0.808 |
IGF2 | P01344 | insulin like growth factor 2 | 4.4E-02 | 0.390 | 0.885 | |
FGFR3 | P22607 | fibroblast growth factor receptor 3 | Kinase | 1.6E-05 | 0.391 | 0.846 |
PTCH1 | Q13635 | patched 1 | 1.00 | 0.398 | 0.885 | |
IGF1R | P08069 | insulin like growth factor 1 receptor | Kinase | 0.97 | 0.399 | 0.885 |
COX8A | P10176 | cytochrome c oxidase subunit 8A | Enzyme | 0.12 | 0.400 | 0.846 |
MECP2 | P51608 | methyl-CpG binding protein 2 | Epigenetic regulator | 0.89 | 0.414 | 0.846 |
FBN1 | P35555 | fibrillin 1 | Calcium-binding protein | 1.00 | 0.417 | 0.846 |
FLNA | P21333 | filamin A | 1.00 | 0.419 | 0.846 | |
DMD | P11532 | dystrophin | 1.00 | 0.423 | 0.923 | |
RAC1 | P63000 | Rac family small GTPase 1 | Enzyme modulator | 0.76 | 0.429 | 0.962 |
NOTCH3 | Q9UM47 | notch receptor 3 | 0.41 | 0.435 | 0.808 | |
COL2A1 | P02458 | collagen type II alpha 1 chain | 1.00 | 0.444 | 0.846 | |
INS | P01308 | insulin | 0.30 | 0.445 | 0.923 | |
SPARC | P09486 | secreted protein acidic and cysteine rich | Signaling | 0.89 | 0.445 | 0.846 |
MMP13 | P45452 | matrix metallopeptidase 13 | Enzyme | 7.9E-18 | 0.452 | 0.923 |
WWOX | Q9NZC7 | WW domain containing oxidoreductase | Enzyme | 1.2E-15 | 0.453 | 0.808 |