Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
LMNA | P02545 | lamin A/C | 1.00 | 0.384 | 0.885 | |
FGFR2 | P21802 | fibroblast growth factor receptor 2 | Kinase | 1.00 | 0.380 | 0.808 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
FBN1 | P35555 | fibrillin 1 | Calcium-binding protein | 1.00 | 0.417 | 0.846 |
MECP2 | P51608 | methyl-CpG binding protein 2 | Epigenetic regulator | 0.89 | 0.414 | 0.846 |
COL2A1 | P02458 | collagen type II alpha 1 chain | 1.00 | 0.444 | 0.846 | |
FGFR3 | P22607 | fibroblast growth factor receptor 3 | Kinase | 1.6E-05 | 0.391 | 0.846 |
FLNA | P21333 | filamin A | 1.00 | 0.419 | 0.846 | |
PTPN11 | Q06124 | protein tyrosine phosphatase non-receptor type 11 | 1.00 | 0.385 | 0.923 | |
PTCH1 | Q13635 | patched 1 | 1.00 | 0.398 | 0.885 | |
SDHD | O14521 | succinate dehydrogenase complex subunit D | Transporter | 0.34 | 0.472 | 0.885 |
GBA | P04062 | glucosylceramidase beta | 1.4E-06 | 0.500 | 0.808 | |
MED12 | Q93074 | mediator complex subunit 12 | Transcription factor | 1.00 | 0.476 | 0.769 |
NRAS | P01111 | NRAS proto-oncogene, GTPase | Enzyme modulator | 0.49 | 0.390 | 0.808 |
FKRP | Q9H9S5 | fukutin related protein | 9.8E-06 | 0.513 | 0.731 | |
SUFU | Q9UMX1 | SUFU negative regulator of hedgehog signaling | 1.00 | 0.493 | 0.769 | |
RYR1 | P21817 | ryanodine receptor 1 | Ion channel | 1.6E-29 | 0.489 | 0.808 |
POMT1 | Q9Y6A1 | protein O-mannosyltransferase 1 | 4.2E-17 | 0.525 | 0.615 | |
TTN | Q8WZ42 | titin | Kinase | 2.6E-96 | 0.470 | 0.885 |
TRPV4 | Q9HBA0 | transient receptor potential cation channel subfamily V member 4 | Ion channel | 2.2E-16 | 0.457 | 0.808 |
RPS6KA3 | P51812 | ribosomal protein S6 kinase A3 | Kinase | 1.00 | 0.491 | 0.846 |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
PIEZO2 | Q9H5I5 | piezo type mechanosensitive ion channel component 2 | Ion channel | 8.1E-07 | 0.529 | 0.769 |
BCOR | Q6W2J9 | BCL6 corepressor | 1.00 | 0.471 | 0.808 | |
SDHB | P21912 | succinate dehydrogenase complex iron sulfur subunit B | Enzyme | 2.4E-04 | 0.474 | 0.846 |