Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
PTCH1 Q13635 patched 1 1.00 0.398 0.885
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808
NOTCH3 Q9UM47 notch receptor 3 0.41 0.435 0.808
MAP2K1 Q02750 mitogen-activated protein kinase kinase 1 Kinase 0.90 0.439 0.846
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885
EP300 Q09472 E1A binding protein p300 1.00 0.459 0.846
RPS6KA3 P51812 ribosomal protein S6 kinase A3 Kinase 1.00 0.491 0.846
SRY Q05066 sex determining region Y Transcription factor 0.456 0.808
ACTG1 P63261 actin gamma 1 Cellular structure 4.8E-03 0.477 0.846
SOS1 Q07889 SOS Ras/Rac guanine nucleotide exchange factor 1 Enzyme modulator 1.00 0.485 0.808
SMC1A Q14683 structural maintenance of chromosomes 1A 1.00 0.509 0.808
TFAP2A P05549 transcription factor AP-2 alpha Transcription factor 0.99 0.488 0.769
HDAC8 Q9BY41 histone deacetylase 8 Epigenetic regulator 0.98 0.511 0.885
NIPBL Q6KC79 NIPBL cohesin loading factor Nucleic acid binding 1.00 0.521 0.808
NSD2 O96028 nuclear receptor binding SET domain protein 2 Epigenetic regulator 1.00 0.507 0.769
CHST3 Q7LGC8 carbohydrate sulfotransferase 3 7.2E-03 0.517 0.846