Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
LMNA P02545 lamin A/C 1.00 0.384 0.885
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
SMARCB1 Q12824 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 Nucleic acid binding 1.00 0.434 0.846
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846
SMARCA4 P51532 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Epigenetic regulator 1.00 0.450 0.885
ARID1A O14497 AT-rich interaction domain 1A 1.00 0.455 0.846
RTEL1 Q9NZ71 regulator of telomere elongation helicase 1 Enzyme 8.9E-10 0.459 0.808
ATR Q13535 ATR serine/threonine kinase Kinase 3.5E-09 0.456 0.923
CBS P0DN79 P35520 cystathionine beta-synthase Enzyme 3.1E-05 0.465 0.885
LIG4 P49917 DNA ligase 4 4.2E-06 0.478 0.846
ARID1B Q8NFD5 AT-rich interaction domain 1B 1.00 0.503 0.846
ZMPSTE24 O75844 zinc metallopeptidase STE24 Enzyme 8.9E-16 0.517 0.731
HDAC4 P56524 histone deacetylase 4 Epigenetic regulator 1.00 0.484 0.885
ERCC3 P19447 ERCC excision repair 3, TFIIH core complex helicase subunit Enzyme 3.4E-11 0.504 0.846
TRPS1 Q9UHF7 transcriptional repressor GATA binding 1 1.00 0.537 0.769
HDAC8 Q9BY41 histone deacetylase 8 Epigenetic regulator 0.98 0.511 0.885
FIG4 Q92562 FIG4 phosphoinositide 5-phosphatase 2.3E-34 0.551 0.731
POLR3A O14802 RNA polymerase III subunit A Enzyme 1.3E-23 0.538 0.769
KAT6B Q8WYB5 lysine acetyltransferase 6B Enzyme 1.00 0.525 0.731
EXT1 Q16394 exostosin glycosyltransferase 1 Enzyme 1.00 0.522 0.769
AHSG P02765 alpha 2-HS glycoprotein Enzyme modulator 3.2E-10 0.506 0.846