Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808
RUNX2 Q13950 RUNX family transcription factor 2 Transcription factor 0.95 0.437 0.846
GLI3 P10071 GLI family zinc finger 3 1.00 0.436 0.846
RAD51 Q06609 RAD51 recombinase 2.7E-02 0.447 0.846
ERCC4 Q92889 ERCC excision repair 4, endonuclease catalytic subunit Enzyme 1.4E-12 0.468 0.846
ATR Q13535 ATR serine/threonine kinase Kinase 3.5E-09 0.456 0.923
LIG4 P49917 DNA ligase 4 4.2E-06 0.478 0.846
NBN O60934 nibrin Nucleic acid binding 2.2E-16 0.467 0.808
PHGDH O43175 phosphoglycerate dehydrogenase Enzyme 1.3E-04 0.484 0.885
PSAT1 Q9Y617 phosphoserine aminotransferase 1 1.1E-08 0.478 0.846
FANCB Q8NB91 FA complementation group B 1.00 0.468 0.769
SUFU Q9UMX1 SUFU negative regulator of hedgehog signaling 1.00 0.493 0.769
FANCD2 Q9BXW9 FA complementation group D2 1.1E-30 0.479 0.885
CDK6 Q00534 cyclin dependent kinase 6 Kinase 0.98 0.471 0.731
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
ERCC6 P0DP91 Q03468 ERCC excision repair 6, chromatin remodeling factor 5.2E-22 0.507 0.808
SETBP1 Q9Y6X0 SET binding protein 1 1.00 0.503 0.808
ARX Q96QS3 aristaless related homeobox 0.91 0.516 0.654
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
SCN2A Q99250 sodium voltage-gated channel alpha subunit 2 Ion channel 1.00 0.518 0.731
MKS1 Q9NXB0 MKS transition zone complex subunit 1 Extracellular structure 3.4E-16 0.505 0.769
BUB1B O60566 BUB1 mitotic checkpoint serine/threonine kinase B Kinase 7.0E-10 0.502 0.808