Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
LMNA | P02545 | lamin A/C | 1.00 | 0.384 | 0.885 | |
POLG | P54098 | DNA polymerase gamma, catalytic subunit | Enzyme | 2.1E-09 | 0.457 | 0.846 |
HSPB1 | P04792 | heat shock protein family B (small) member 1 | 2.8E-07 | 0.436 | 0.808 | |
PMP22 | Q01453 | peripheral myelin protein 22 | Cellular structure | 0.91 | 0.471 | 0.885 |
MFN2 | O95140 | mitofusin 2 | Enzyme | 0.99 | 0.471 | 0.846 |
MPZ | P25189 | myelin protein zero | 0.27 | 0.503 | 0.846 | |
NEFL | P07196 | neurofilament light | 0.488 | 0.769 | ||
TYMP | P19971 | thymidine phosphorylase | Enzyme | 1.2E-04 | 0.495 | 0.769 |
RRM2B | Q7LG56 | ribonucleotide reductase regulatory TP53 inducible subunit M2B | Enzyme | 2.4E-03 | 0.527 | 0.769 |
GJB1 | P08034 | gap junction protein beta 1 | Cell-cell junction | 0.85 | 0.514 | 0.731 |
FIG4 | Q92562 | FIG4 phosphoinositide 5-phosphatase | 2.3E-34 | 0.551 | 0.731 | |
FXN | Q16595 | frataxin | Enzyme | 0.34 | 0.510 | 0.654 |
KIF1B | O60333 | kinesin family member 1B | Cellular structure | 1.00 | 0.516 | 0.808 |
SIGMAR1 | Q99720 | sigma non-opioid intracellular receptor 1 | 0.17 | 0.544 | 0.808 | |
DYNC1H1 | Q14204 | dynein cytoplasmic 1 heavy chain 1 | Enzyme | 1.00 | 0.547 | 0.769 |
HK1 | P19367 | hexokinase 1 | Kinase | 0.91 | 0.542 | 0.731 |
NALCN | Q8IZF0 | sodium leak channel, non-selective | Ion channel | 8.5E-14 | 0.587 | 0.615 |
SETX | Q7Z333 | senataxin | Enzyme | 0.95 | 0.570 | 0.731 |
EGR2 | P11161 | early growth response 2 | Nucleic acid binding | 0.50 | 0.547 | 0.769 |
GJC2 | Q5T442 | gap junction protein gamma 2 | Cell-cell junction | 1.0E-02 | 0.593 | 0.692 |
MED25 | Q71SY5 | mediator complex subunit 25 | Transcription factor | 8.4E-07 | 0.582 | 0.654 |
SACS | Q9NZJ4 | sacsin molecular chaperone | 1.1E-23 | 0.606 | 0.654 | |
SLC12A6 | Q9UHW9 | solute carrier family 12 member 6 | Transporter | 1.1E-02 | 0.603 | 0.500 |
GDAP1 | Q8TB36 | ganglioside induced differentiation associated protein 1 | 3.2E-08 | 0.612 | 0.538 | |
RAB7A | P51149 | RAB7A, member RAS oncogene family | 0.97 | 0.597 | 0.692 |