Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
ACTB | P60709 | actin beta | Cellular structure | 0.99 | 0.325 | 0.923 |
LMNA | P02545 | lamin A/C | 1.00 | 0.384 | 0.885 | |
PTPN11 | Q06124 | protein tyrosine phosphatase non-receptor type 11 | 1.00 | 0.385 | 0.923 | |
SLC2A1 | P11166 | solute carrier family 2 member 1 | Transporter | 0.99 | 0.388 | 0.808 |
MECP2 | P51608 | methyl-CpG binding protein 2 | Epigenetic regulator | 0.89 | 0.414 | 0.846 |
FLNA | P21333 | filamin A | 1.00 | 0.419 | 0.846 | |
KMT2A | Q03164 | lysine methyltransferase 2A | 1.00 | 0.410 | 0.885 | |
HLA-DQB1 | P01920 | major histocompatibility complex, class II, DQ beta 1 | Immune response | 8.9E-03 | 0.407 | 0.885 |
SOX2 | P48431 | SRY-box transcription factor 2 | Transcription factor | 0.71 | 0.405 | 0.808 |
INSR | P06213 | insulin receptor | Kinase | 3.6E-05 | 0.432 | 0.846 |
CREBBP | Q92793 | CREB binding protein | 1.00 | 0.428 | 0.808 | |
HLA-DQA1 | P01909 | major histocompatibility complex, class II, DQ alpha 1 | Immune response | 2.4E-02 | 0.416 | 0.846 |
CHD7 | Q9P2D1 | chromodomain helicase DNA binding protein 7 | 1.00 | 0.441 | 0.846 | |
ATRX | P46100 | ATRX chromatin remodeler | 1.00 | 0.452 | 0.808 | |
MAP2K1 | Q02750 | mitogen-activated protein kinase kinase 1 | Kinase | 0.90 | 0.439 | 0.846 |
TCF4 | P15884 | transcription factor 4 | Transcription factor | 1.00 | 0.464 | 0.846 |
EP300 | Q09472 | E1A binding protein p300 | 1.00 | 0.459 | 0.846 | |
CDC42 | P60953 | cell division cycle 42 | Enzyme modulator | 0.79 | 0.458 | 0.846 |
RTEL1 | Q9NZ71 | regulator of telomere elongation helicase 1 | Enzyme | 8.9E-10 | 0.459 | 0.808 |
ATR | Q13535 | ATR serine/threonine kinase | Kinase | 3.5E-09 | 0.456 | 0.923 |
KMT2D | O14686 | lysine methyltransferase 2D | 1.00 | 0.465 | 0.808 | |
CDKN1C | P49918 | cyclin dependent kinase inhibitor 1C | 0.82 | 0.456 | 0.846 | |
LIG4 | P49917 | DNA ligase 4 | 4.2E-06 | 0.478 | 0.846 |