Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
CASR P41180 calcium sensing receptor G-protein coupled receptor 4.7E-02 0.410 0.846
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808
PDGFRB P09619 platelet derived growth factor receptor beta Kinase 0.90 0.416 0.846
TNFRSF1B P20333 TNF receptor superfamily member 1B 0.50 0.425 0.885
NOTCH3 Q9UM47 notch receptor 3 0.41 0.435 0.808
CD28 P10747 CD28 molecule 0.36 0.436 0.885
RAD51 Q06609 RAD51 recombinase 2.7E-02 0.447 0.846
ERCC4 Q92889 ERCC excision repair 4, endonuclease catalytic subunit Enzyme 1.4E-12 0.468 0.846
FANCB Q8NB91 FA complementation group B 1.00 0.468 0.769
LBR Q14739 lamin B receptor Enzyme 0.18 0.473 0.808
SDHB P21912 succinate dehydrogenase complex iron sulfur subunit B Enzyme 2.4E-04 0.474 0.846
COL3A1 P02461 collagen type III alpha 1 chain 1.00 0.477 0.808
FANCD2 Q9BXW9 FA complementation group D2 1.1E-30 0.479 0.885
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
IKBKG Q9Y6K9 inhibitor of nuclear factor kappa B kinase regulatory subunit gamma Kinase 8.5E-02 0.493 0.769