Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
PTCH1 Q13635 patched 1 1.00 0.398 0.885
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
ELN P15502 elastin 2.1E-14 0.415 0.885
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
TGFB2 P61812 transforming growth factor beta 2 Signaling 1.00 0.433 0.885
TGFBR1 P36897 transforming growth factor beta receptor 1 Kinase 0.85 0.451 0.885
MED12 Q93074 mediator complex subunit 12 Transcription factor 1.00 0.476 0.769
LOX P28300 lysyl oxidase 0.99 0.447 0.846
CDC42 P60953 cell division cycle 42 Enzyme modulator 0.79 0.458 0.846
SUFU Q9UMX1 SUFU negative regulator of hedgehog signaling 1.00 0.493 0.769
SOS1 Q07889 SOS Ras/Rac guanine nucleotide exchange factor 1 Enzyme modulator 1.00 0.485 0.808
TGFB3 P10600 transforming growth factor beta 3 Signaling 0.99 0.498 0.808
PIEZO2 Q9H5I5 piezo type mechanosensitive ion channel component 2 Ion channel 8.1E-07 0.529 0.769
ACTA2 P62736 actin alpha 2, smooth muscle Cellular structure 0.93 0.508 0.846
MYLK Q15746 myosin light chain kinase Kinase 9.2E-12 0.510 0.846
HUWE1 Q7Z6Z7 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 Enzyme 1.00 0.534 0.769
RIT1 Q92963 Ras like without CAAX 1 Enzyme modulator 0.13 0.527 0.808
ABCC6 O95255 ATP binding cassette subfamily C member 6 Transporter 5.6E-35 0.540 0.654
MAP2K2 P36507 mitogen-activated protein kinase kinase 2 Kinase 0.97 0.534 0.731
MYH11 P35749 myosin heavy chain 11 0.77 0.528 0.731
CEP120 Q8N960 centrosomal protein 120 4.1E-15 0.564 0.731