Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
SETD2 Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 1.00 0.424 0.846
TSC2 P49815 TSC complex subunit 2 Enzyme modulator 1.00 0.439 0.808
GLI3 P10071 GLI family zinc finger 3 1.00 0.436 0.846
TSC1 Q92574 TSC complex subunit 1 1.00 0.440 0.808
TCF4 P15884 transcription factor 4 Transcription factor 1.00 0.464 0.846
MED12 Q93074 mediator complex subunit 12 Transcription factor 1.00 0.476 0.769
RPS6KA3 P51812 ribosomal protein S6 kinase A3 Kinase 1.00 0.491 0.846
BCOR Q6W2J9 BCL6 corepressor 1.00 0.471 0.808
LIG4 P49917 DNA ligase 4 4.2E-06 0.478 0.846
SUFU Q9UMX1 SUFU negative regulator of hedgehog signaling 1.00 0.493 0.769
DHCR7 Q9UBM7 7-dehydrocholesterol reductase Enzyme 3.9E-13 0.500 0.846
OFD1 O75665 OFD1 centriole and centriolar satellite protein 0.96 0.510 0.808
LRP2 P98164 LDL receptor related protein 2 1.00 0.491 0.846
ARX Q96QS3 aristaless related homeobox 0.91 0.516 0.654
NSD1 Q96L73 nuclear receptor binding SET domain protein 1 Epigenetic regulator 1.00 0.505 0.769
PEX1 O43933 peroxisomal biogenesis factor 1 1.1E-14 0.538 0.769
MKS1 Q9NXB0 MKS transition zone complex subunit 1 Extracellular structure 3.4E-16 0.505 0.769
BUB1B O60566 BUB1 mitotic checkpoint serine/threonine kinase B Kinase 7.0E-10 0.502 0.808
FOXG1 P55316 forkhead box G1 0.94 0.522 0.692
AHI1 Q8N157 Abelson helper integration site 1 1.1E-25 0.513 0.846