| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
|---|---|---|---|---|---|---|
| AKT1 | P31749 | AKT serine/threonine kinase 1 | Kinase | 0.98 | 0.311 | 0.962 |
| ATM | Q13315 | ATM serine/threonine kinase | Kinase | 5.6E-47 | 0.374 | 0.885 |
| BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
| BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
| BUB1 | O43683 | BUB1 mitotic checkpoint serine/threonine kinase | Kinase | 4.9E-09 | 0.528 | 0.731 |
| BUB1B | O60566 | BUB1 mitotic checkpoint serine/threonine kinase B | Kinase | 7.0E-10 | 0.502 | 0.808 |
| CIB1 | Q99828 | calcium and integrin binding 1 | 3.3E-04 | 0.458 | 0.769 | |
| GNAS | O95467 P63092 P84996 Q5JWF2 | GNAS complex locus | Enzyme modulator | 0.68 | 0.420 | 0.885 |
| KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
| MAP2K1 | Q02750 | mitogen-activated protein kinase kinase 1 | Kinase | 0.90 | 0.439 | 0.846 |
| MRC1 | P22897 | mannose receptor C-type 1 | 0.94 | 0.413 | 0.846 | |
| MSH2 | P43246 | mutS homolog 2 | Nucleic acid binding | 0.90 | 0.406 | 0.808 |
| NF1 | P21359 | neurofibromin 1 | Enzyme modulator | 0.90 | 0.440 | 0.885 |
| NF2 | P35240 | neurofibromin 2 | 1.00 | 0.468 | 0.885 | |
| PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
| PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
| RAD51 | Q06609 | RAD51 recombinase | 2.7E-02 | 0.447 | 0.846 | |
| SDHC | Q99643 | succinate dehydrogenase complex subunit C | 2.0E-04 | 0.517 | 0.846 | |
| SDHD | O14521 | succinate dehydrogenase complex subunit D | Transporter | 0.34 | 0.472 | 0.885 |
| TP63 | Q9H3D4 | tumor protein p63 | Transcription factor | 1.00 | 0.362 | 0.769 |
| TSC2 | P49815 | TSC complex subunit 2 | Enzyme modulator | 1.00 | 0.439 | 0.808 |