Disease: Motor Neuron Disease
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CHMP2B Q9UQN3 charged multivesicular body protein 2B 4.6E-06 0.543 0.731
DCDC2 Q9UHG0 doublecortin domain containing 2 5.7E-10 0.546 0.769
UBQLN2 Q9UHD9 ubiquilin 2 0.85 0.656 0.462
TBK1 Q9UHD2 TANK binding kinase 1 Kinase 7.5E-02 0.513 0.846
VPS54 Q9P1Q0 VPS54 subunit of GARP complex Transporter 1.00 0.769 0.231
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
OPTN Q96CV9 optineurin 5.9E-18 0.548 0.808
FIG4 Q92562 FIG4 phosphoinositide 5-phosphatase 2.3E-34 0.551 0.731
CHCHD10 Q8WYQ3 coiled-coil-helix-coiled-coil-helix domain containing 10 5.4E-06 0.623 0.462
ARHGEF28 Q8N1W1 Rho guanine nucleotide exchange factor 28 8.1E-21 0.615 0.423
SARM1 Q6SZW1 sterile alpha and TIR motif containing 1 1.7E-10 0.682 0.346
DCTN1 Q14203 dynactin subunit 1 Chaperone 8.4E-02 0.597 0.500
TARDBP Q13148 TAR DNA binding protein 0.99 0.493 0.808
FKBP1A P62942 FKBP prolyl isomerase 1A Enzyme 0.81 0.641 0.654
VCP P55072 valosin containing protein 1.00 0.469 0.923
SLC1A2 P43004 solute carrier family 1 member 2 Transporter 0.71 0.511 0.731
PRPH P41219 peripherin 4.8E-14 0.623 0.462
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885
CNTF P26441 ciliary neurotrophic factor 2.3E-05 0.561 0.615
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
HGF P14210 hepatocyte growth factor Enzyme 1.00 0.374 0.885
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
NEFH P12036 neurofilament heavy 2.7E-12 0.588 0.769