Disease: Frontotemporal Lobar Degeneration
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962
CHMP2B Q9UQN3 charged multivesicular body protein 2B 4.6E-06 0.543 0.731
CST3 P01034 cystatin C 3.9E-03 0.436 0.808
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
DCTN1 Q14203 dynactin subunit 1 Chaperone 8.4E-02 0.597 0.500
EWSR1 Q01844 EWS RNA binding protein 1 Nucleic acid binding 1.00 0.474 0.692
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
HSF1 Q00613 heat shock transcription factor 1 Transcription factor 0.75 0.507 0.769
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
INA Q16352 internexin neuronal intermediate filament protein alpha 1.5E-08 0.633 0.500
MATR3 P43243 matrin 3 1.00 0.631 0.538
NEFL P07196 neurofilament light 0.488 0.769
OPTN Q96CV9 optineurin 5.9E-18 0.548 0.808
PFN1 P07737 profilin 1 0.73 0.565 0.769
SNCG O76070 synuclein gamma Transporter 8.5E-04 0.550 0.615
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
SS18L1 O75177 SS18L1 subunit of BAF chromatin remodeling complex Nucleic acid binding 0.98 0.670 0.538
TAF15 Q92804 TATA-box binding protein associated factor 15 Nucleic acid binding 0.17 0.626 0.500
TARDBP Q13148 TAR DNA binding protein 0.99 0.493 0.808
TBK1 Q9UHD2 TANK binding kinase 1 Kinase 7.5E-02 0.513 0.846
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
UBQLN2 Q9UHD9 ubiquilin 2 0.85 0.656 0.462