Disease: Motor Neuron Disease
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ALS2 Q96Q42 alsin Rho guanine nucleotide exchange factor ALS2 8.7E-12 0.647 0.423
ANG P03950 angiogenin 0.29 0.511 0.769
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
ARHGEF28 Q8N1W1 Rho guanine nucleotide exchange factor 28 8.1E-21 0.615 0.423
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962
CNTF P26441 ciliary neurotrophic factor 2.3E-05 0.561 0.615
DCTN1 Q14203 dynactin subunit 1 Chaperone 8.4E-02 0.597 0.500
DYNC1H1 Q14204 dynein cytoplasmic 1 heavy chain 1 Enzyme 1.00 0.547 0.769
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
GRIA2 P42262 glutamate ionotropic receptor AMPA type subunit 2 Ion channel 1.00 0.573 0.692
GRM2 Q14416 glutamate metabotropic receptor 2 G-protein coupled receptor 0.12 0.582 0.577
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
HGF P14210 hepatocyte growth factor Enzyme 1.00 0.374 0.885
HNRNPA3 P51991 heterogeneous nuclear ribonucleoprotein A3 1.00 0.751 0.308
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
NEFH P12036 neurofilament heavy 2.7E-12 0.588 0.769
OPTN Q96CV9 optineurin 5.9E-18 0.548 0.808
PFN1 P07737 profilin 1 0.73 0.565 0.769
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885
PRPH P41219 peripherin 4.8E-14 0.623 0.462