Disease: Motor neuron atrophy
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ALS2 Q96Q42 alsin Rho guanine nucleotide exchange factor ALS2 8.7E-12 0.647 0.423
APEX1 P27695 apurinic/apyrimidinic endodeoxyribonuclease 1 1.9E-07 0.458 0.846
ATXN1 P54253 ataxin 1 0.97 0.534 0.769
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CNTF P26441 ciliary neurotrophic factor 2.3E-05 0.561 0.615
CSNK1E P49674 casein kinase 1 epsilon 1.00 0.619 0.615
CST3 P01034 cystatin C 3.9E-03 0.436 0.808
DCTN1 Q14203 dynactin subunit 1 Chaperone 8.4E-02 0.597 0.500
DYNC1H1 Q14204 dynein cytoplasmic 1 heavy chain 1 Enzyme 1.00 0.547 0.769
ERBB4 Q15303 erb-b2 receptor tyrosine kinase 4 Kinase 1.00 0.455 0.846
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
MIR375 microRNA 375 0.476 0.769
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
NEFH P12036 neurofilament heavy 2.7E-12 0.588 0.769
OPTN Q96CV9 optineurin 5.9E-18 0.548 0.808
PFN1 P07737 profilin 1 0.73 0.565 0.769
PRPH P41219 peripherin 4.8E-14 0.623 0.462
SARM1 Q6SZW1 sterile alpha and TIR motif containing 1 1.7E-10 0.682 0.346
SETX Q7Z333 senataxin Enzyme 0.95 0.570 0.731
SLC1A2 P43004 solute carrier family 1 member 2 Transporter 0.71 0.511 0.731
SMN1 Q16637 survival of motor neuron 1, telomeric Epigenetic regulator 1.6E-02 0.454 0.769
SMN2 Q16637 survival of motor neuron 2, centromeric 0.10 0.459 0.769