Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
ACTB | P60709 | actin beta | Cellular structure | 0.99 | 0.325 | 0.923 |
MAPK1 | P28482 | mitogen-activated protein kinase 1 | Kinase | 1.00 | 0.330 | 0.923 |
MTOR | P42345 | mechanistic target of rapamycin kinase | Kinase | 1.00 | 0.343 | 0.885 |
PTPN11 | Q06124 | protein tyrosine phosphatase non-receptor type 11 | 1.00 | 0.385 | 0.923 | |
MECP2 | P51608 | methyl-CpG binding protein 2 | Epigenetic regulator | 0.89 | 0.414 | 0.846 |
SMAD4 | Q13485 | SMAD family member 4 | Transcription factor | 1.00 | 0.401 | 0.808 |
IGF1R | P08069 | insulin like growth factor 1 receptor | Kinase | 0.97 | 0.399 | 0.885 |
FBN1 | P35555 | fibrillin 1 | Calcium-binding protein | 1.00 | 0.417 | 0.846 |
KMT2A | Q03164 | lysine methyltransferase 2A | 1.00 | 0.410 | 0.885 | |
ATN1 | P54259 | atrophin 1 | 1.00 | 0.409 | 0.885 | |
PDGFRB | P09619 | platelet derived growth factor receptor beta | Kinase | 0.90 | 0.416 | 0.846 |
DMD | P11532 | dystrophin | 1.00 | 0.423 | 0.923 | |
SYT1 | P21579 | synaptotagmin 1 | Transporter | 0.60 | 0.412 | 0.846 |
CREBBP | Q92793 | CREB binding protein | 1.00 | 0.428 | 0.808 | |
BMP2 | P12643 | bone morphogenetic protein 2 | Signaling | 0.99 | 0.432 | 0.846 |
ATRX | P46100 | ATRX chromatin remodeler | 1.00 | 0.452 | 0.808 | |
GJB2 | P29033 | gap junction protein beta 2 | Cell-cell junction | 6.6E-16 | 0.441 | 0.846 |
BCR | P11274 | BCR activator of RhoGEF and GTPase | Enzyme modulator | 0.99 | 0.431 | 0.885 |
WNT5A | P41221 | Wnt family member 5A | Signaling | 0.99 | 0.443 | 0.808 |
EP300 | Q09472 | E1A binding protein p300 | 1.00 | 0.459 | 0.846 | |
MED12 | Q93074 | mediator complex subunit 12 | Transcription factor | 1.00 | 0.476 | 0.769 |
CDC42 | P60953 | cell division cycle 42 | Enzyme modulator | 0.79 | 0.458 | 0.846 |
RPS6KA3 | P51812 | ribosomal protein S6 kinase A3 | Kinase | 1.00 | 0.491 | 0.846 |
ACTG1 | P63261 | actin gamma 1 | Cellular structure | 4.8E-03 | 0.477 | 0.846 |