Disease: Lymphangioleiomyomatosis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VEGFC P49767 vascular endothelial growth factor C Signaling 0.50 0.459 0.769
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
SMN2 Q16637 survival of motor neuron 2, centromeric 0.10 0.459 0.769
SMN1 Q16637 survival of motor neuron 1, telomeric Epigenetic regulator 1.6E-02 0.454 0.769
RNF19A Q9NV58 ring finger protein 19A, RBR E3 ubiquitin protein ligase Enzyme 2.5E-02 0.397 0.923
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
POLDIP2 Q9Y2S7 DNA polymerase delta interacting protein 2 0.41 0.396 0.923
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923
PDPN Q86YL7 podoplanin 3.2E-04 0.470 0.769
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885
MIR21 microRNA 21 0.363 0.846
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
IGFBP2 P18065 insulin like growth factor binding protein 2 Enzyme modulator 0.12 0.478 0.769
GRAP2 O75791 GRB2 related adaptor protein 2 1.5E-04 0.394 0.923
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923
CRK P46108 CRK proto-oncogene, adaptor protein 0.96 0.394 0.923