Disease: ECTRODACTYLY, ECTODERMAL DYSPLASIA, AND CLEFT LIP/PALATE SYNDROME 1
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
UVRAG Q9P2Y5 UV radiation resistance associated 0.99 0.436 0.769
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
S100A6 P06703 S100 calcium binding protein A6 Calcium-binding protein 0.18 0.510 0.808
RNF19A Q9NV58 ring finger protein 19A, RBR E3 ubiquitin protein ligase Enzyme 2.5E-02 0.397 0.923
RPE65 Q16518 retinoid isomerohydrolase RPE65 Enzyme 6.5E-14 0.417 0.808
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MIR429 microRNA 429 0.544 0.731
MIR200C microRNA 200c 0.486 0.846
MIR200A microRNA 200a 0.519 0.808
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885
IL6 P05231 interleukin 6 0.32 0.248 0.962
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
GRAP2 O75791 GRB2 related adaptor protein 2 1.5E-04 0.394 0.923