Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
GABPA Q06546 GA binding protein transcription factor subunit alpha Transcription factor 1.00 0.379 0.885
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
RPE65 Q16518 retinoid isomerohydrolase RPE65 Enzyme 6.5E-14 0.417 0.808
RNF19A Q9NV58 ring finger protein 19A, RBR E3 ubiquitin protein ligase Enzyme 2.5E-02 0.397 0.923
S100A6 P06703 S100 calcium binding protein A6 Calcium-binding protein 0.18 0.510 0.808
CRK P46108 CRK proto-oncogene, adaptor protein 0.96 0.394 0.923