Disease: ECTRODACTYLY, ECTODERMAL DYSPLASIA, AND CLEFT LIP/PALATE SYNDROME 1
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MIR200A microRNA 200a 0.519 0.808
MIR200C microRNA 200c 0.486 0.846
MIR429 microRNA 429 0.544 0.731
RPE65 Q16518 retinoid isomerohydrolase RPE65 Enzyme 6.5E-14 0.417 0.808
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923
GRAP2 O75791 GRB2 related adaptor protein 2 1.5E-04 0.394 0.923
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
AIMP2 Q13155 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 8.0E-03 0.393 0.923
RNF19A Q9NV58 ring finger protein 19A, RBR E3 ubiquitin protein ligase Enzyme 2.5E-02 0.397 0.923
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
S100A6 P06703 S100 calcium binding protein A6 Calcium-binding protein 0.18 0.510 0.808
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
IL6 P05231 interleukin 6 0.32 0.248 0.962
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923
POLDIP2 Q9Y2S7 DNA polymerase delta interacting protein 2 0.41 0.396 0.923
CKAP4 Q07065 cytoskeleton associated protein 4 0.51 0.436 0.731
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CRK P46108 CRK proto-oncogene, adaptor protein 0.96 0.394 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
UVRAG Q9P2Y5 UV radiation resistance associated 0.99 0.436 0.769