FOS |
P01100
|
Fos proto-oncogene, AP-1 transcription factor subunit
|
Transcription factor
|
0.26 |
0.411 |
0.885 |
HIF1A |
Q16665
|
hypoxia inducible factor 1 subunit alpha
|
Transcription factor
|
0.98 |
0.327 |
0.923 |
MYC |
P01106
|
MYC proto-oncogene, bHLH transcription factor
|
Transcription factor
|
1.00 |
0.344 |
0.923 |
ZEB1 |
P37275
|
zinc finger E-box binding homeobox 1
|
Transcription factor
|
0.97 |
0.442 |
0.808 |
TP53 |
P04637
|
tumor protein p53
|
Transcription factor
|
0.53 |
0.236 |
0.962 |
TP63 |
Q9H3D4
|
tumor protein p63
|
Transcription factor
|
1.00 |
0.362 |
0.769 |
BCL2 |
P10415
|
BCL2 apoptosis regulator
|
Signaling
|
0.56 |
0.291 |
0.885 |
CCN2 |
P29279
|
cellular communication network factor 2
|
Signaling
|
5.0E-04 |
0.399 |
0.846 |
FGF2 |
P09038
|
fibroblast growth factor 2
|
Signaling
|
1.8E-02 |
0.383 |
0.923 |
CXCL8 |
P10145
|
C-X-C motif chemokine ligand 8
|
Signaling
|
2.7E-04 |
0.310 |
0.962 |
SPARC |
P09486
|
secreted protein acidic and cysteine rich
|
Signaling
|
0.89 |
0.445 |
0.846 |
TNF |
P01375
|
tumor necrosis factor
|
Signaling
|
0.80 |
0.231 |
0.962 |
VEGFA |
P15692
|
vascular endothelial growth factor A
|
Signaling
|
2.4E-05 |
0.266 |
0.923 |
MDM2 |
Q00987
|
MDM2 proto-oncogene
|
Nucleic acid binding
|
1.00 |
0.362 |
0.846 |
PCNA |
P12004
|
proliferating cell nuclear antigen
|
Nucleic acid binding
|
0.98 |
0.382 |
0.846 |
AKT1 |
P31749
|
AKT serine/threonine kinase 1
|
Kinase
|
0.98 |
0.311 |
0.962 |
EGFR |
P00533
|
epidermal growth factor receptor
|
Kinase
|
0.37 |
0.295 |
0.885 |
MTOR |
P42345
|
mechanistic target of rapamycin kinase
|
Kinase
|
1.00 |
0.343 |
0.885 |
PDGFRA |
P16234
|
platelet derived growth factor receptor alpha
|
Kinase
|
1.00 |
0.415 |
0.808 |
MAPK1 |
P28482
|
mitogen-activated protein kinase 1
|
Kinase
|
1.00 |
0.330 |
0.923 |
MMP1 |
P03956
|
matrix metallopeptidase 1
|
Enzyme
|
7.7E-18 |
0.385 |
0.885 |
MMP2 |
P08253
|
matrix metallopeptidase 2
|
Enzyme
|
0.84 |
0.333 |
0.923 |
MMP9 |
P14780
|
matrix metallopeptidase 9
|
Enzyme
|
1.9E-17 |
0.305 |
0.923 |
PTGS2 |
P35354
|
prostaglandin-endoperoxide synthase 2
|
Enzyme
|
1.00 |
0.314 |
0.962 |
RPE65 |
Q16518
|
retinoid isomerohydrolase RPE65
|
Enzyme
|
6.5E-14 |
0.417 |
0.808 |