Disease: Congenital Abnormality
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
GABPA Q06546 GA binding protein transcription factor subunit alpha Transcription factor 1.00 0.379 0.885
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
IRF6 O14896 interferon regulatory factor 6 Transcription factor 1.00 0.486 0.769
SMAD7 O15105 SMAD family member 7 Transcription factor 0.55 0.470 0.769
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
TCF4 P15884 transcription factor 4 Transcription factor 1.00 0.464 0.846
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TWIST1 Q15672 twist family bHLH transcription factor 1 Transcription factor 0.34 0.397 0.846
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
ZEB2 O60315 zinc finger E-box binding homeobox 2 Transcription factor 1.00 0.471 0.808
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
RIPK4 P57078 receptor interacting serine/threonine kinase 4 Kinase 4.0E-03 0.565 0.654