Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
ACTB | P60709 | actin beta | Cellular structure | 0.99 | 0.325 | 0.923 |
MAPK1 | P28482 | mitogen-activated protein kinase 1 | Kinase | 1.00 | 0.330 | 0.923 |
PTPN11 | Q06124 | protein tyrosine phosphatase non-receptor type 11 | 1.00 | 0.385 | 0.923 | |
PTCH1 | Q13635 | patched 1 | 1.00 | 0.398 | 0.885 | |
IGF1R | P08069 | insulin like growth factor 1 receptor | Kinase | 0.97 | 0.399 | 0.885 |
KMT2A | Q03164 | lysine methyltransferase 2A | 1.00 | 0.410 | 0.885 | |
CREBBP | Q92793 | CREB binding protein | 1.00 | 0.428 | 0.808 | |
CHD7 | Q9P2D1 | chromodomain helicase DNA binding protein 7 | 1.00 | 0.441 | 0.846 | |
RAC1 | P63000 | Rac family small GTPase 1 | Enzyme modulator | 0.76 | 0.429 | 0.962 |
BCR | P11274 | BCR activator of RhoGEF and GTPase | Enzyme modulator | 0.99 | 0.431 | 0.885 |
EHMT1 | Q9H9B1 | euchromatic histone lysine methyltransferase 1 | Epigenetic regulator | 1.00 | 0.460 | 0.808 |
EP300 | Q09472 | E1A binding protein p300 | 1.00 | 0.459 | 0.846 | |
CDC42 | P60953 | cell division cycle 42 | Enzyme modulator | 0.79 | 0.458 | 0.846 |
KMT2D | O14686 | lysine methyltransferase 2D | 1.00 | 0.465 | 0.808 | |
RPS6KA3 | P51812 | ribosomal protein S6 kinase A3 | Kinase | 1.00 | 0.491 | 0.846 |
BCOR | Q6W2J9 | BCL6 corepressor | 1.00 | 0.471 | 0.808 | |
ACTG1 | P63261 | actin gamma 1 | Cellular structure | 4.8E-03 | 0.477 | 0.846 |
OFD1 | O75665 | OFD1 centriole and centriolar satellite protein | 0.96 | 0.510 | 0.808 | |
HDAC4 | P56524 | histone deacetylase 4 | Epigenetic regulator | 1.00 | 0.484 | 0.885 |
SMC1A | Q14683 | structural maintenance of chromosomes 1A | 1.00 | 0.509 | 0.808 | |
NSD1 | Q96L73 | nuclear receptor binding SET domain protein 1 | Epigenetic regulator | 1.00 | 0.505 | 0.769 |
SOX11 | P35716 | SRY-box transcription factor 11 | Transcription factor | 0.86 | 0.494 | 0.808 |
KDM6A | O15550 | lysine demethylase 6A | Epigenetic regulator | 1.00 | 0.498 | 0.769 |
HDAC8 | Q9BY41 | histone deacetylase 8 | Epigenetic regulator | 0.98 | 0.511 | 0.885 |
MKS1 | Q9NXB0 | MKS transition zone complex subunit 1 | Extracellular structure | 3.4E-16 | 0.505 | 0.769 |