Disease: Hypopigmentation disorder
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AP3B1 O00203 adaptor related protein complex 3 subunit beta 1 Transporter 0.62 0.619 0.808
BACE1 P56817 beta-secretase 1 Enzyme 0.88 0.559 0.769
CABIN1 Q9Y6J0 calcineurin binding protein 1 Enzyme modulator 3.3E-17 0.536 0.846
CLCN7 P51798 chloride voltage-gated channel 7 Ion channel 0.27 0.590 0.731
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
CXCL11 O14625 C-X-C motif chemokine ligand 11 Signaling 0.31 0.519 0.808
DCT P40126 dopachrome tautomerase Enzyme 7.4E-14 0.619 0.654
DKK1 O94907 dickkopf WNT signaling pathway inhibitor 1 0.17 0.439 0.885
EPG5 Q9HCE0 ectopic P-granules autophagy protein 5 homolog 1.4E-13 0.623 0.769
FGL1 Q08830 fibrinogen like 1 Signaling 1.7E-25 0.638 0.692
FIG4 Q92562 FIG4 phosphoinositide 5-phosphatase 2.3E-34 0.551 0.731
FSCN1 Q16658 fascin actin-bundling protein 1 Cellular structure 0.87 0.504 0.731
GABRB3 P28472 gamma-aminobutyric acid type A receptor subunit beta3 Ion channel 0.95 0.546 0.615
GLI3 P10071 GLI family zinc finger 3 1.00 0.436 0.846
GPR143 P51810 G protein-coupled receptor 143 G-protein coupled receptor 0.93 0.659 0.385
HDAC5 Q9UQL6 histone deacetylase 5 Epigenetic regulator 1.00 0.552 0.769
HPS1 Q92902 HPS1 biogenesis of lysosomal organelles complex 3 subunit 1 1.3E-07 0.636 0.692
HPS3 Q969F9 HPS3 biogenesis of lysosomal organelles complex 2 subunit 1 2.9E-21 0.769 0.308
HPS5 Q9UPZ3 HPS5 biogenesis of lysosomal organelles complex 2 subunit 2 1.9E-13 0.674 0.423
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
LTBR P36941 lymphotoxin beta receptor 0.31 0.592 0.692
MC1R Q01726 melanocortin 1 receptor G-protein coupled receptor 8.1E-11 0.524 0.808
MITF O75030 melanocyte inducing transcription factor 0.98 0.499 0.808
MLANA Q16655 melan-A 1.3E-09 0.579 0.692
MLPH Q9BV36 melanophilin Cellular structure 4.4E-10 0.743 0.423