Disease: Childhood Myelodysplastic Syndrome
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MIR378A microRNA 378a 0.532 0.808
DNMT3A Q9Y6K1 DNA methyltransferase 3 alpha 7.4E-39 0.445 0.846
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808
MLF1 P58340 myeloid leukemia factor 1 Signaling 4.4E-09 0.666 0.385
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
FHL2 Q14192 four and a half LIM domains 2 Transcription factor 2.9E-05 0.556 0.731
OPRK1 P41145 opioid receptor kappa 1 G-protein coupled receptor 4.1E-05 0.555 0.615
HOXA9 P31269 homeobox A9 4.4E-05 0.521 0.692
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
CSF1R P07333 colony stimulating factor 1 receptor Kinase 0.13 0.448 0.808
TNFSF10 P50591 TNF superfamily member 10 Signaling 0.13 0.413 0.885
S100A8 P05109 S100 calcium binding protein A8 Calcium-binding protein 0.14 0.430 0.962
CDH1 P12830 cadherin 1 0.15 0.401 0.808
GFI1 Q99684 growth factor independent 1 transcriptional repressor Transcription factor 0.25 0.546 0.769
CSF3 P09919 colony stimulating factor 3 0.38 0.377 0.885
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
CEBPA P49715 CCAAT enhancer binding protein alpha Transcription factor 0.55 0.496 0.692
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
FLT3 P36888 fms related receptor tyrosine kinase 3 Kinase 0.61 0.462 0.654
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
LYL1 P12980 LYL1 basic helix-loop-helix family member Transcription factor 0.77 0.670 0.192