Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
VWF P04275 von Willebrand factor Enzyme modulator 3.2E-25 0.408 0.885
ELN P15502 elastin 2.1E-14 0.415 0.885
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
JAG1 P78504 jagged canonical Notch ligand 1 1.00 0.429 0.808
BMP2 P12643 bone morphogenetic protein 2 Signaling 0.99 0.432 0.846
MAP2K1 Q02750 mitogen-activated protein kinase kinase 1 Kinase 0.90 0.439 0.846
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885
CHD7 Q9P2D1 chromodomain helicase DNA binding protein 7 1.00 0.441 0.846
NOTCH2 Q04721 notch receptor 2 1.00 0.441 0.808
GATA4 P43694 GATA binding protein 4 0.49 0.458 0.846
CDC42 P60953 cell division cycle 42 Enzyme modulator 0.79 0.458 0.846
GPC3 P51654 glypican 3 1.00 0.466 0.808
TTN Q8WZ42 titin Kinase 2.6E-96 0.470 0.885
BCOR Q6W2J9 BCL6 corepressor 1.00 0.471 0.808
ZEB2 O60315 zinc finger E-box binding homeobox 2 Transcription factor 1.00 0.471 0.808
IGFBP7 Q16270 insulin like growth factor binding protein 7 1.3E-03 0.476 0.769