Disease: Childhood Acute Lymphoblastic Leukemia
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
ARID5B Q14865 AT-rich interaction domain 5B Transcription factor 1.00 0.638 0.500
ARNT P27540 aryl hydrocarbon receptor nuclear translocator Transcription factor 1.00 0.575 0.692
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923
CDK6 Q00534 cyclin dependent kinase 6 Kinase 0.98 0.471 0.731
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CEBPE Q15744 CCAAT enhancer binding protein epsilon Transcription factor 7.1E-03 0.674 0.385
CRLF2 Q9HC73 cytokine receptor like factor 2 Signaling 3.3E-07 0.615 0.538
CYP1A2 P05177 cytochrome P450 family 1 subfamily A member 2 Enzyme 2.5E-10 0.494 0.923
CYP1B1 Q16678 cytochrome P450 family 1 subfamily B member 1 Enzyme 2.2E-05 0.457 0.769
CYP2C8 P10632 cytochrome P450 family 2 subfamily C member 8 2.0E-22 0.615 0.615
CYP2E1 P05181 cytochrome P450 family 2 subfamily E member 1 8.1E-09 0.459 0.885
DUX4 Q9UBX2 double homeobox 4 0.604 0.500
EPHX1 P07099 epoxide hydrolase 1 3.2E-09 0.500 0.846
ERG P11308 ETS transcription factor ERG Transcription factor 0.96 0.453 0.808
ETV6 P41212 ETS variant transcription factor 6 Transcription factor 0.97 0.477 0.731
FLT3 P36888 fms related receptor tyrosine kinase 3 Kinase 0.61 0.462 0.654
FPGS Q05932 folylpolyglutamate synthase Enzyme 1.2E-06 0.644 0.423
GNB1 P62873 G protein subunit beta 1 Enzyme 1.00 0.617 0.731
HCK P08631 HCK proto-oncogene, Src family tyrosine kinase Kinase 2.0E-02 0.663 0.500
HLF Q16534 HLF transcription factor, PAR bZIP family member Nucleic acid binding 0.95 0.628 0.615
HOXD4 P09016 homeobox D4 5.4E-03 0.760 0.346
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808