Disease: Delayed bone age
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
CHD7 Q9P2D1 chromodomain helicase DNA binding protein 7 1.00 0.441 0.846
DDB2 Q92466 damage specific DNA binding protein 2 Nucleic acid binding 7.4E-06 0.576 0.654
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
ERCC3 P19447 ERCC excision repair 3, TFIIH core complex helicase subunit Enzyme 3.4E-11 0.504 0.846
ERCC4 Q92889 ERCC excision repair 4, endonuclease catalytic subunit Enzyme 1.4E-12 0.468 0.846
ERCC5 P28715 ERCC excision repair 5, endonuclease 2.7E-13 0.499 0.731
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885
GTF2E2 P29084 general transcription factor IIE subunit 2 Transcription factor 3.9E-02 0.617 0.692
GTF2H5 Q6ZYL4 general transcription factor IIH subunit 5 4.5E-02 0.556 0.769
HESX1 Q9UBX0 HESX homeobox 1 8.0E-04 0.561 0.654
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846
KIF15 Q9NS87 kinesin family member 15 Cellular structure 9.5E-25 0.617 0.654
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
LIG4 P49917 DNA ligase 4 4.2E-06 0.478 0.846
MBTPS2 O43462 membrane bound transcription factor peptidase, site 2 Enzyme 1.00 0.513 0.769
MPLKIP Q8TAP9 M-phase specific PLK1 interacting protein 1.6E-04 0.604 0.654
NSUN2 Q08J23 NOP2/Sun RNA methyltransferase 2 Enzyme 2.6E-04 0.559 0.846
OTX2 P32243 orthodenticle homeobox 2 Transcription factor 0.92 0.514 0.808
PAX8 Q06710 paired box 8 1.00 0.477 0.731
PCNT O95613 pericentrin 4.0E-58 0.564 0.808
PPP2R3C Q969Q6 protein phosphatase 2 regulatory subunit B''gamma Enzyme 6.8E-09 0.700 0.538
PROKR2 Q8NFJ6 prokineticin receptor 2 G-protein coupled receptor 2.4E-06 0.538 0.731
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885