Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808
RAD51 Q06609 RAD51 recombinase 2.7E-02 0.447 0.846
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
ELANE P08246 elastase, neutrophil expressed Enzyme 1.2E-03 0.447 0.846
ERCC4 Q92889 ERCC excision repair 4, endonuclease catalytic subunit Enzyme 1.4E-12 0.468 0.846
TERC telomerase RNA component 0.471 0.846
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808
LIG4 P49917 DNA ligase 4 4.2E-06 0.478 0.846
FANCB Q8NB91 FA complementation group B 1.00 0.468 0.769
FANCD2 Q9BXW9 FA complementation group D2 1.1E-30 0.479 0.885
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
RPS19 P39019 ribosomal protein S19 Nucleic acid binding 0.92 0.480 0.846
RECQL4 O94761 RecQ like helicase 4 Enzyme 3.3E-35 0.496 0.808
BUB1B O60566 BUB1 mitotic checkpoint serine/threonine kinase B Kinase 7.0E-10 0.502 0.808