Disease: Dejerine-Sottas Disease (disorder)
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
GORASP1 Q9BQQ3 golgi reassembly stacking protein 1 2.0E-02 0.428 0.846
GPR4 P46093 G protein-coupled receptor 4 G-protein coupled receptor 0.10 0.674 0.462
GPX2 P18283 glutathione peroxidase 2 Enzyme 1.5E-04 0.619 0.500
IFNG P01579 interferon gamma 0.47 0.288 0.962
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
MAPK8 P45983 mitogen-activated protein kinase 8 Kinase 1.00 0.397 0.885
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923
MPZ P25189 myelin protein zero 0.27 0.503 0.846
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
NR0B1 P51843 nuclear receptor subfamily 0 group B member 1 Nuclear receptor 0.97 0.494 0.808
OCLN Q16625 occludin 8.6E-07 0.507 0.846
PMP22 Q01453 peripheral myelin protein 22 Cellular structure 0.91 0.471 0.885
RELA Q04206 RELA proto-oncogene, NF-kB subunit Transcription factor 1.00 0.406 0.885
RIPK3 Q9Y572 receptor interacting serine/threonine kinase 3 Kinase 1.2E-14 0.497 0.885
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
SYT1 P21579 synaptotagmin 1 Transporter 0.60 0.412 0.846
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TNFSF15 O95150 TNF superfamily member 15 Signaling 2.8E-03 0.531 0.692
WNK1 Q9H4A3 WNK lysine deficient protein kinase 1 Kinase 1.00 0.416 0.846