Source: CLINVAR ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
AXIN1 O15169 axin 1 0.41 0.559 0.577
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
IDH2 P48735 isocitrate dehydrogenase (NADP(+)) 2 0.88 0.434 0.808
CNOT9 Q92600 CCR4-NOT transcription complex subunit 9 0.99 0.769 0.192
RXRA P19793 retinoid X receptor alpha Nuclear receptor 1.00 0.543 0.769
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
SF3B2 Q13435 splicing factor 3b subunit 2 1.00 0.780 0.308
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
SF3B1 O75533 splicing factor 3b subunit 1 Nucleic acid binding 1.00 0.511 0.731
IGF2R P11717 insulin like growth factor 2 receptor Receptor 1.00 0.518 0.731