Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
VEGFA | P15692 | vascular endothelial growth factor A | Signaling | 2.4E-05 | 0.266 | 0.923 |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
MTHFR | P42898 | methylenetetrahydrofolate reductase | 3.2E-10 | 0.337 | 0.885 | |
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
PPARG | P37231 | peroxisome proliferator activated receptor gamma | Nuclear receptor | 2.9E-02 | 0.358 | 0.885 |
SERPINE1 | P05121 | serpin family E member 1 | Enzyme modulator | 4.4E-02 | 0.359 | 0.885 |
HMGB1 | P09429 | high mobility group box 1 | Nucleic acid binding | 0.82 | 0.368 | 0.923 |
FAS | P25445 | Fas cell surface death receptor | 0.81 | 0.372 | 0.923 | |
EDN1 | P05305 | endothelin 1 | Signaling | 0.46 | 0.380 | 0.846 |
JAK2 | O60674 | Janus kinase 2 | Kinase | 0.65 | 0.385 | 0.885 |
G6PD | P11413 | glucose-6-phosphate dehydrogenase | Enzyme | 0.97 | 0.424 | 0.846 |
EDNRA | P25101 | endothelin receptor type A | G-protein coupled receptor | 0.99 | 0.426 | 0.885 |
HFE | Q30201 | homeostatic iron regulator | 2.6E-08 | 0.436 | 0.846 | |
TFRC | P02786 | transferrin receptor | Enzyme | 7.0E-05 | 0.437 | 0.885 |
ANGPT1 | Q15389 | angiopoietin 1 | Signaling | 0.95 | 0.446 | 0.808 |
CD36 | P16671 | CD36 molecule | Receptor | 1.1E-60 | 0.446 | 0.846 |
P2RX7 | Q99572 | purinergic receptor P2X 7 | Ion channel | 3.3E-11 | 0.450 | 0.808 |
PPARGC1A | Q9UBK2 | PPARG coactivator 1 alpha | Transcription factor | 1.00 | 0.453 | 0.885 |
EPAS1 | Q99814 | endothelial PAS domain protein 1 | Transcription factor | 0.60 | 0.454 | 0.731 |
HNF4A | P41235 | hepatocyte nuclear factor 4 alpha | Nuclear receptor | 0.15 | 0.461 | 0.808 |
CYP17A1 | P05093 | cytochrome P450 family 17 subfamily A member 1 | 2.6E-04 | 0.462 | 0.769 | |
PLA2G6 | O60733 | phospholipase A2 group VI | Enzyme modulator | 2.5E-10 | 0.476 | 0.846 |
PML | P29590 | promyelocytic leukemia | 0.21 | 0.477 | 0.846 |