Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
MYC | P01106 | MYC proto-oncogene, bHLH transcription factor | Transcription factor | 1.00 | 0.344 | 0.923 |
TLR2 | O60603 | toll like receptor 2 | 1.0E-06 | 0.361 | 0.923 | |
EZH2 | Q15910 | enhancer of zeste 2 polycomb repressive complex 2 subunit | Epigenetic regulator | 1.00 | 0.376 | 0.885 |
EPO | P01588 | erythropoietin | 1.1E-02 | 0.381 | 0.885 | |
POLG | P54098 | DNA polymerase gamma, catalytic subunit | Enzyme | 2.1E-09 | 0.457 | 0.846 |
CDKN2B | P42772 | cyclin dependent kinase inhibitor 2B | 7.3E-03 | 0.417 | 0.769 | |
CREBBP | Q92793 | CREB binding protein | 1.00 | 0.428 | 0.808 | |
HFE | Q30201 | homeostatic iron regulator | 2.6E-08 | 0.436 | 0.846 | |
RUNX1 | Q01196 | RUNX family transcription factor 1 | Transcription factor | 0.65 | 0.425 | 0.808 |
ATRX | P46100 | ATRX chromatin remodeler | 1.00 | 0.452 | 0.808 | |
EGR1 | P18146 | early growth response 1 | Nucleic acid binding | 0.35 | 0.433 | 0.923 |
TET2 | Q6N021 | tet methylcytosine dioxygenase 2 | 4.3E-54 | 0.458 | 0.808 | |
BMI1 | P35226 | BMI1 proto-oncogene, polycomb ring finger | 0.94 | 0.448 | 0.808 | |
BAP1 | Q92560 | BRCA1 associated protein 1 | Enzyme | 0.99 | 0.454 | 0.731 |
ASXL1 | Q8IXJ9 | ASXL transcriptional regulator 1 | 1.3E-14 | 0.482 | 0.808 | |
NPM1 | P06748 | nucleophosmin 1 | Chaperone | 1.00 | 0.464 | 0.846 |
HDAC1 | Q13547 | histone deacetylase 1 | Epigenetic regulator | 0.61 | 0.460 | 0.846 |
GATA1 | P15976 | GATA binding protein 1 | 0.95 | 0.483 | 0.808 | |
DAPK1 | P53355 | death associated protein kinase 1 | Kinase | 1.00 | 0.472 | 0.808 |
SPHK1 | Q9NYA1 | sphingosine kinase 1 | Kinase | 3.0E-07 | 0.480 | 0.808 |
GATA2 | P23769 | GATA binding protein 2 | 0.98 | 0.496 | 0.654 | |
CFLAR | O15519 | CASP8 and FADD like apoptosis regulator | Enzyme | 1.00 | 0.485 | 0.846 |
SF3B1 | O75533 | splicing factor 3b subunit 1 | Nucleic acid binding | 1.00 | 0.511 | 0.731 |