Disease: Childhood Myelodysplastic Syndrome
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808
ATG7 O95352 autophagy related 7 Enzyme 7.4E-12 0.505 0.769
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808
BMI1 P35226 BMI1 proto-oncogene, polycomb ring finger 0.94 0.448 0.808
CDKN2B P42772 cyclin dependent kinase inhibitor 2B 7.3E-03 0.417 0.769
CFLAR O15519 CASP8 and FADD like apoptosis regulator Enzyme 1.00 0.485 0.846
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808
CTNNA1 P35221 catenin alpha 1 Cellular structure 0.97 0.584 0.538
DAPK1 P53355 death associated protein kinase 1 Kinase 1.00 0.472 0.808
DLK1 P80370 delta like non-canonical Notch ligand 1 Signaling 3.5E-02 0.527 0.692
EGR1 P18146 early growth response 1 Nucleic acid binding 0.35 0.433 0.923
EPO P01588 erythropoietin 1.1E-02 0.381 0.885
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885
GATA1 P15976 GATA binding protein 1 0.95 0.483 0.808
GATA2 P23769 GATA binding protein 2 0.98 0.496 0.654
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
LYL1 P12980 LYL1 basic helix-loop-helix family member Transcription factor 0.77 0.670 0.192
NPM1 P06748 nucleophosmin 1 Chaperone 1.00 0.464 0.846
PLCB1 Q9NQ66 phospholipase C beta 1 Enzyme 0.98 0.595 0.654
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
SF3B1 O75533 splicing factor 3b subunit 1 Nucleic acid binding 1.00 0.511 0.731
SRSF2 Q01130 serine and arginine rich splicing factor 2 Nucleic acid binding 0.48 0.561 0.731
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962