Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923
PTCH1 Q13635 patched 1 1.00 0.398 0.885
TSC2 P49815 TSC complex subunit 2 Enzyme modulator 1.00 0.439 0.808
PAK1 Q13153 p21 (RAC1) activated kinase 1 Kinase 1.3E-03 0.494 0.808
AKT3 Q9Y243 AKT serine/threonine kinase 3 Kinase 1.00 0.512 0.808
HMMR O75330 hyaluronan mediated motility receptor 5.5E-21 0.544 0.615
PIK3R2 O00459 phosphoinositide-3-kinase regulatory subunit 2 Enzyme modulator 1.6E-02 0.551 0.808
CASP2 P42575 caspase 2 Enzyme 1.5E-03 0.565 0.731
MLC1 Q15049 modulator of VRAC current 1 Ion channel 3.2E-08 0.585 0.769
CRADD P78560 CASP2 and RIPK1 domain containing adaptor with death domain 0.88 0.619 0.500
RHEB Q15382 Ras homolog, mTORC1 binding Enzyme modulator 0.98 0.631 0.577
HERC1 Q15751 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 Enzyme modulator 1.00 0.674 0.500
RNASET2 O00584 ribonuclease T2 2.7E-04 0.682 0.615
MAST1 Q9Y2H9 microtubule associated serine/threonine kinase 1 Kinase 1.00 0.711 0.385
TBC1D7 Q9P0N9 TBC1 domain family member 7 2.9E-12 0.729 0.385