Disease: Juvenile Myelomonocytic Leukemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885
CBLL2 Q8N7E2 Cbl proto-oncogene like 2 Enzyme 0.476 0.808
CCR7 P32248 C-C motif chemokine receptor 7 G-protein coupled receptor 5.8E-02 0.443 0.769
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808
CD38 P28907 CD38 molecule Enzyme 2.3E-06 0.407 0.885
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CDKN2D P55273 cyclin dependent kinase inhibitor 2D 0.49 0.547 0.769
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885
F9 P00740 coagulation factor IX Enzyme 1.00 0.465 0.885
FANCB Q8NB91 FA complementation group B 1.00 0.468 0.769
FLT3 P36888 fms related receptor tyrosine kinase 3 Kinase 0.61 0.462 0.654
GATA2 P23769 GATA binding protein 2 0.98 0.496 0.654
H3P13 H3 histone pseudogene 13 0.584 0.769
HOXA9 P31269 homeobox A9 4.4E-05 0.521 0.692
IL18R1 Q13478 interleukin 18 receptor 1 Receptor 8.6E-06 0.473 0.808
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL23A Q9NPF7 interleukin 23 subunit alpha Signaling 0.36 0.415 0.846
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885
MECOM Q03112 MDS1 and EVI1 complex locus 1.00 0.513 0.731
MUL1 Q969V5 mitochondrial E3 ubiquitin protein ligase 1 1.9E-06 0.473 0.808