Disease: MIXED LINEAGE LEUKEMIA
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ALOX5 P09917 arachidonate 5-lipoxygenase Enzyme 1.2E-06 0.447 0.885
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
ASB2 Q96Q27 ankyrin repeat and SOCS box containing 2 6.8E-15 0.769 0.308
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRD4 O60885 bromodomain containing 4 Epigenetic regulator 1.00 0.446 0.885
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923
CBLL2 Q8N7E2 Cbl proto-oncogene like 2 Enzyme 0.476 0.808
CCR7 P32248 C-C motif chemokine receptor 7 G-protein coupled receptor 5.8E-02 0.443 0.769
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808
CD38 P28907 CD38 molecule Enzyme 2.3E-06 0.407 0.885
CDK1 P06493 cyclin dependent kinase 1 Kinase 0.99 0.482 0.808
CDKN1B P46527 cyclin dependent kinase inhibitor 1B 0.62 0.409 0.769
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885
FLT3 P36888 fms related receptor tyrosine kinase 3 Kinase 0.61 0.462 0.654
HDAC1 Q13547 histone deacetylase 1 Epigenetic regulator 0.61 0.460 0.846
HDAC9 Q9UKV0 histone deacetylase 9 Epigenetic regulator 1.00 0.439 0.846
HOXA9 P31269 homeobox A9 4.4E-05 0.521 0.692
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885
LGALS1 P09382 galectin 1 Signaling 4.5E-03 0.435 0.846
MAPK8 P45983 mitogen-activated protein kinase 8 Kinase 1.00 0.397 0.885
MECOM Q03112 MDS1 and EVI1 complex locus 1.00 0.513 0.731