Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
RAD51 Q06609 RAD51 recombinase 2.7E-02 0.447 0.846
MMP13 P45452 matrix metallopeptidase 13 Enzyme 7.9E-18 0.452 0.923
ERCC4 Q92889 ERCC excision repair 4, endonuclease catalytic subunit Enzyme 1.4E-12 0.468 0.846
SHH Q15465 sonic hedgehog signaling molecule 0.98 0.461 0.846
FANCB Q8NB91 FA complementation group B 1.00 0.468 0.769
FANCD2 Q9BXW9 FA complementation group D2 1.1E-30 0.479 0.885
DHCR7 Q9UBM7 7-dehydrocholesterol reductase Enzyme 3.9E-13 0.500 0.846
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
HOXD13 P35453 homeobox D13 8.6E-03 0.483 0.808
RECQL4 O94761 RecQ like helicase 4 Enzyme 3.3E-35 0.496 0.808
TPM2 P07951 tropomyosin 2 Cellular structure 2.4E-04 0.530 0.654
FANCC Q00597 FA complementation group C 2.8E-13 0.507 0.808
FANCA O15360 FA complementation group A 1.6E-68 0.505 0.731
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731
XRCC2 O43543 X-ray repair cross complementing 2 4.0E-07 0.512 0.731
TBX5 Q99593 T-box transcription factor 5 Transcription factor 1.00 0.528 0.769
RAD51C O43502 RAD51 paralog C 6.2E-14 0.533 0.692
MYH3 P11055 myosin heavy chain 3 6.7E-21 0.563 0.654
ZBTB16 Q05516 zinc finger and BTB domain containing 16 Transcription factor 1.00 0.545 0.808
FANCF Q9NPI8 FA complementation group F 0.46 0.535 0.731