Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |
IL6 | P05231 | interleukin 6 | 0.32 | 0.248 | 0.962 | |
IL1B | P01584 | interleukin 1 beta | 0.13 | 0.276 | 0.962 | |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
PIK3CD | O00329 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | Kinase | 1.00 | 0.319 | 0.885 |
PIK3CG | P48736 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | Kinase | 1.4E-06 | 0.320 | 0.885 |
PIK3CB | P42338 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta | Kinase | 1.00 | 0.322 | 0.885 |
HMGB1 | P09429 | high mobility group box 1 | Nucleic acid binding | 0.82 | 0.368 | 0.923 |
IL1RN | P18510 | interleukin 1 receptor antagonist | 3.1E-02 | 0.373 | 0.923 | |
AGER | Q15109 | advanced glycosylation end-product specific receptor | Receptor | 6.4E-16 | 0.420 | 0.885 |
JAG1 | P78504 | jagged canonical Notch ligand 1 | 1.00 | 0.429 | 0.808 | |
RUNX2 | Q13950 | RUNX family transcription factor 2 | Transcription factor | 0.95 | 0.437 | 0.846 |
MMP13 | P45452 | matrix metallopeptidase 13 | Enzyme | 7.9E-18 | 0.452 | 0.923 |
NOX4 | Q9NPH5 | NADPH oxidase 4 | Enzyme | 5.8E-20 | 0.471 | 0.885 |
MOK | Q9UQ07 | MOK protein kinase | Kinase | 8.8E-22 | 0.476 | 0.769 |
GREM1 | O60565 | gremlin 1, DAN family BMP antagonist | 0.47 | 0.508 | 0.808 | |
ELF3 | P78545 | E74 like ETS transcription factor 3 | Transcription factor | 0.98 | 0.551 | 0.808 |
ACLY | P53396 | ATP citrate lyase | Enzyme | 8.4E-02 | 0.563 | 0.692 |
DOT1L | Q8TEK3 | DOT1 like histone lysine methyltransferase | Epigenetic regulator | 1.00 | 0.599 | 0.692 |
PRG4 | Q92954 | proteoglycan 4 | 1.7E-08 | 0.601 | 0.615 | |
LXN | Q9BS40 | latexin | 1.8E-06 | 0.633 | 0.615 | |
FGF18 | O76093 | fibroblast growth factor 18 | Signaling | 0.39 | 0.647 | 0.577 |