Disease: 46, XY Disorders of Sex Development
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CYP11A1 P05108 cytochrome P450 family 11 subfamily A member 1 5.5E-07 0.547 0.731
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808
GART P22102 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase Enzyme 2.8E-04 0.631 0.615
PAICS P22234 phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase Enzyme 2.8E-05 0.711 0.346
LHCGR P22888 luteinizing hormone/choriogonadotropin receptor G-protein coupled receptor 5.3E-08 0.528 0.692
SRD5A2 P31213 steroid 5 alpha-reductase 2 Enzyme 0.564 0.615
HSD17B3 P37058 hydroxysteroid 17-beta dehydrogenase 3 8.5E-07 0.641 0.346
SOX9 P48436 SRY-box transcription factor 9 1.00 0.419 0.846
HSD17B7 P56937 hydroxysteroid 17-beta dehydrogenase 7 6.6E-06 0.582 0.500
EMX2 Q04743 empty spiracles homeobox 2 Transcription factor 0.95 0.623 0.577
SRY Q05066 sex determining region Y Transcription factor 0.456 0.808
MAP3K1 Q13233 mitogen-activated protein kinase kinase kinase 1 Kinase 1.00 0.538 0.731
NR5A1 Q13285 nuclear receptor subfamily 5 group A member 1 Nuclear receptor 0.99 0.479 0.731
MAMLD1 Q13495 mastermind like domain containing 1 0.63 0.650 0.500
CBX2 Q14781 chromobox 2 Epigenetic regulator 1.00 0.674 0.269
SAMD9 Q5K651 sterile alpha motif domain containing 9 1.1E-33 0.606 0.808
DHRS11 Q6UWP2 dehydrogenase/reductase 11 Enzyme 2.2E-06 0.653 0.423
HSD17B13 Q7Z5P4 hydroxysteroid 17-beta dehydrogenase 13 2.7E-05 0.623 0.538
ZFPM2 Q8WW38 zinc finger protein, FOG family member 2 Transcription factor 1.00 0.565 0.731
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923