Disease: estrogen receptor-negative breast cancer
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CDH1 P12830 cadherin 1 0.15 0.401 0.808
CYP17A1 P05093 cytochrome P450 family 17 subfamily A member 1 2.6E-04 0.462 0.769
CYP19A1 P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 1.7E-05 0.410 0.885
CYP1A1 P04798 cytochrome P450 family 1 subfamily A member 1 Enzyme 1.1E-17 0.436 0.846
CYP1B1 Q16678 cytochrome P450 family 1 subfamily B member 1 Enzyme 2.2E-05 0.457 0.769
EMSY Q7Z589 EMSY transcriptional repressor, BRCA2 interacting 1.00 0.628 0.423
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
GSTK1 Q9Y2Q3 glutathione S-transferase kappa 1 1.9E-06 0.412 0.885
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923
HOXB13 Q92826 homeobox B13 3.7E-08 0.573 0.462
INCENP Q9NQS7 inner centromere protein 0.89 0.700 0.346
MAD1L1 Q9Y6D9 mitotic arrest deficient 1 like 1 6.8E-16 0.570 0.731
MAP2K1 Q02750 mitogen-activated protein kinase kinase 1 Kinase 0.90 0.439 0.846
MECOM Q03112 MDS1 and EVI1 complex locus 1.00 0.513 0.731
MMP14 P50281 matrix metallopeptidase 14 Enzyme 1.00 0.447 0.769
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885
PSAT1 Q9Y617 phosphoserine aminotransferase 1 1.1E-08 0.478 0.846
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
SLCO6A1 Q86UG4 solute carrier organic anion transporter family member 6A1 Transporter 2.9E-11 0.412 0.885