Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
ATM | Q13315 | ATM serine/threonine kinase | Kinase | 5.6E-47 | 0.374 | 0.885 |
MLH1 | P40692 | mutL homolog 1 | Nucleic acid binding | 3.4E-05 | 0.399 | 0.808 |
CDH1 | P12830 | cadherin 1 | 0.15 | 0.401 | 0.808 | |
MSH2 | P43246 | mutS homolog 2 | Nucleic acid binding | 0.90 | 0.406 | 0.808 |
CDKN1B | P46527 | cyclin dependent kinase inhibitor 1B | 0.62 | 0.409 | 0.769 | |
SMARCA4 | P51532 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | Epigenetic regulator | 1.00 | 0.450 | 0.885 |
CHEK2 | O96017 | checkpoint kinase 2 | Kinase | 1.2E-24 | 0.460 | 0.808 |
MSH6 | P52701 | mutS homolog 6 | Nucleic acid binding | 3.7E-05 | 0.462 | 0.731 |
PALB2 | Q86YC2 | partner and localizer of BRCA2 | 3.0E-19 | 0.485 | 0.769 | |
MSH3 | P20585 | mutS homolog 3 | Nucleic acid binding | 7.4E-31 | 0.474 | 0.769 |
PMS2 | P54278 | PMS1 homolog 2, mismatch repair system component | Nucleic acid binding | 4.5E-27 | 0.484 | 0.808 |
EPHX1 | P07099 | epoxide hydrolase 1 | 3.2E-09 | 0.500 | 0.846 | |
XRCC4 | Q13426 | X-ray repair cross complementing 4 | 8.3E-07 | 0.528 | 0.769 | |
SEMA4A | Q9H3S1 | semaphorin 4A | Signaling | 1.8E-05 | 0.569 | 0.692 |
MLH3 | Q9UHC1 | mutL homolog 3 | Nucleic acid binding | 4.9E-08 | 0.582 | 0.538 |
FBXO11 | Q86XK2 | F-box protein 11 | Enzyme | 1.00 | 0.604 | 0.692 |
FAN1 | Q9Y2M0 | FANCD2 and FANCI associated nuclease 1 | 1.7E-25 | 0.610 | 0.577 | |
EXO1 | Q9UQ84 | exonuclease 1 | Enzyme | 8.1E-13 | 0.578 | 0.692 |
RPS20 | P60866 | ribosomal protein S20 | Nucleic acid binding | 2.1E-02 | 0.610 | 0.692 |
CTNNA1 | P35221 | catenin alpha 1 | Cellular structure | 0.97 | 0.584 | 0.538 |
PTPRJ | Q12913 | protein tyrosine phosphatase receptor type J | Enzyme | 1.3E-11 | 0.606 | 0.615 |
BARD1 | Q99728 | BRCA1 associated RING domain 1 | 1.4E-24 | 0.597 | 0.538 | |
RAD51D | O75771 | RAD51 paralog D | 1.1E-09 | 0.674 | 0.385 | |
NFKBIZ | Q9BYH8 | NFKB inhibitor zeta | 1.00 | 0.674 | 0.577 |