Disease: PACHYONYCHIA CONGENITA 3
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
KLK3 P07288 kallikrein related peptidase 3 Enzyme 4.4E-06 0.443 0.885
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
NPEPPS P55786 aminopeptidase puromycin sensitive Enzyme 1.00 0.519 0.808
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PLAG1 Q6DJT9 PLAG1 zinc finger Transcription factor 1.00 0.493 0.808
PRKAA1 Q13131 protein kinase AMP-activated catalytic subunit alpha 1 Kinase 0.14 0.453 0.846
PRKAA2 P54646 protein kinase AMP-activated catalytic subunit alpha 2 Kinase 3.5E-08 0.456 0.846
PRKAB1 Q9Y478 protein kinase AMP-activated non-catalytic subunit beta 1 Kinase 5.3E-03 0.460 0.846
PROS1 P07225 protein S 4.7E-04 0.467 0.846
PSAT1 Q9Y617 phosphoserine aminotransferase 1 1.1E-08 0.478 0.846
RUNX2 Q13950 RUNX family transcription factor 2 Transcription factor 0.95 0.437 0.846
SERPINF1 P36955 serpin family F member 1 Enzyme modulator 7.8E-08 0.460 0.846
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962