Disease: Congenital Abnormality
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
ACVR1 Q04771 activin A receptor type 1 Kinase 0.33 0.535 0.731
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
EED O75530 embryonic ectoderm development 1.00 0.588 0.615
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
NOG Q13253 noggin 0.89 0.518 0.731
NTRK1 P04629 neurotrophic receptor tyrosine kinase 1 Kinase 2.0E-06 0.422 0.808
PAX3 P23760 paired box 3 0.24 0.481 0.769
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PTCH1 Q13635 patched 1 1.00 0.398 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
REST Q13127 RE1 silencing transcription factor Transcription factor 0.99 0.535 0.808
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TP53BP1 Q12888 tumor protein p53 binding protein 1 Epigenetic regulator 1.00 0.520 0.731
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808