Disease: High grade glioma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACVR1 Q04771 activin A receptor type 1 Kinase 0.33 0.535 0.731
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
CD276 Q5ZPR3 CD276 molecule Enzyme modulator 2.5E-09 0.505 0.731
CDK7 P50613 cyclin dependent kinase 7 Kinase 4.5E-07 0.566 0.731
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
H3-3A P84243 H3.3 histone A 0.12 0.559 0.692
H3-3B P84243 H3.3 histone B 0.81 0.599 0.385
IL4R P24394 interleukin 4 receptor Receptor 2.3E-04 0.474 0.846
KDM6B O15054 lysine demethylase 6B Epigenetic regulator 1.00 0.514 0.808
MELK Q14680 maternal embryonic leucine zipper kinase Kinase 4.5E-22 0.566 0.577
NLGN3 Q9NZ94 neuroligin 3 0.98 0.653 0.462
NTRK1 P04629 neurotrophic receptor tyrosine kinase 1 Kinase 2.0E-06 0.422 0.808
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
TNC P24821 tenascin C 1.3E-07 0.433 0.846
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
WEE1 P30291 WEE1 G2 checkpoint kinase Kinase 1.00 0.545 0.769