Disease: Sporadic Breast Carcinoma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
XRCC3 O43542 X-ray repair cross complementing 3 1.9E-10 0.505 0.769
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
ALDH1A1 P00352 aldehyde dehydrogenase 1 family member A1 Enzyme 0.95 0.460 0.846
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
IFNG P01579 interferon gamma 0.47 0.288 0.962
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
PGR P06401 progesterone receptor Nuclear receptor 5.1E-02 0.426 0.885
ERCC1 P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 1.6E-07 0.445 0.846
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CDK4 P11802 cyclin dependent kinase 4 Kinase 6.3E-02 0.412 0.808
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
XRCC1 P18887 X-ray repair cross complementing 1 6.3E-09 0.421 0.923
NFKB1 P19838 nuclear factor kappa B subunit 1 Transcription factor 1.00 0.396 0.923
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CDK2 P24941 cyclin dependent kinase 2 Kinase 0.61 0.456 0.692
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923