Disease: Ichthyosis, X-Linked
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CA9 Q16790 carbonic anhydrase 9 1.3E-09 0.483 0.731
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ERCC1 P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 1.6E-07 0.445 0.846
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
FOXP3 Q9BZS1 forkhead box P3 0.99 0.368 0.846
HPSE Q9Y251 heparanase Enzyme 2.3E-14 0.425 0.808
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
HSPB2 Q16082 heat shock protein family B (small) member 2 3.3E-04 0.457 0.769
HSPB3 Q12988 heat shock protein family B (small) member 3 6.1E-05 0.448 0.769
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IL6 P05231 interleukin 6 0.32 0.248 0.962
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
MUC1 P15941 mucin 1, cell surface associated 1.9E-02 0.384 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923